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Interstate 65 (abbreviated I-65) is an Interstate Highway in the United States. Its southern terminus is at an intersection with Interstate 10 in Mobile, Alabama; its northern terminus is at a traffic light with U.S. Route 12 and U.S. Route 20 (Dunes Highway) in Gary, Indiana, southeast of Chicago, Illinois.
I-65 is known as "Auto Alley" due to the large number of automotive OEM and supplier firms that have facilities within an hour's drive of the highway. Of these, the most notable is the GM plant in Bowling Green, Kentucky.